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Sunday, 28 January 2018

Fat soluble vitamins


FAT SOLUBLE VITAMIN CHART
VitaminMetabolic FunctionDeficiencyToxicityFood SourceOther
Vitamin A
Retinol,
retinal,
retinoic acid,
precursor is
beta-carotene
PromotesVision; maintenance of cornea, epithelial cells, maintain mucous membranes, skin; Promotes bone and tooth growth; reproduction; immunity(Bone)(RBP)infectious diseases, night blindness, blindness (xerophthalmia), keratinization. Hypovitaminosis A.
Dry mucosa (infecton
Abnormal growth (in children)
Reduced bone mineral density, liver abnormalities, birth defects. Hypervitaminosis A.Retinol: milk and milk products
Beta-carotene:
-dark -grean leafy
-deep -yellow/orange vegetables (carrots:)
2001 RDA: Men: 900 mcg REA/day
Woman: 700 mcg REA/day
UL: adults 3000 mcg/day
Vitamin D
ergocalciferol,
cholecalciferol,
calcidiol,
calcitriol
RBP - transport Retinol
Binding
Protein
Help maintain blood Ca levels
Mineralization of bones (raises blood calcium & phosphorus by increasing absorption of Ca from intestine, withdrawing calcium from bones, stimulating retention of Ca by kidneys)
Rickets (inadequate mineralization of bones), osteomalacia (bone disease characterized by softening of bones; symptoms bending spine
& bowing legs)
Calcium imbalance(calcification of soft tissues and formation of stones)Synthesized in body with help of sunshinefortified milk, animal(not meat) eggs1997 AI: adults: 5 mcg/day (19-50 yr)
10 mcg/day (51-70 yr)
15 mcg/day (>70 yr)
UL: adults 50 mcg/day ~2000 IU
Vitamin E
alpha-tocopherol
Antioxidant
-regulation of oxidation
-stablize cell membranes,- reactions
-protection of polyunsaturated
fatty acids (PUFA)
-Protection of vitamin A
functions as a chain - breaks antioxidant that prevents the propagation of free radical reaction
Erythrocyte hemolysis
(breaking open of red blood cells),
-nerve damage.
neuromuscular problem
Hemorrhagic effects;
-enhances effects of anticlotting medication
Vegetable oils; leafy greens vegetables (spinach, turnip greens, collard greens, broccoli), wheat germ, whole grains egg yolks, nuts, seeds, fatty meats.2000 RDA: adults: 15 mg/day
UL: adults 1000 mg/day
*Easily destroyed by heat and oxygen.
Vitamin K
Phylloquinone, menaquinone, menadione, naphthoquinone
Synthesis of blood-clotting proteins and bone proteins
important in normal bone health.
Hemorrhaging
primary not likely secondar possible secondary deficiency from impaired absorption due to the lack of bile salts
None knownSynthesis by GI bacteria; liver, leafy green vegetables, cabbage-type vegetables; milk

made by bacteria in the intestine.bacterial synthesis in gi-tract
not stable undersun light, but stable during cooking
Vit. A Retinol Biniding Protein: Specific protein responsible for transporting retinol from liver in the blood.
Vit. A Mucus Membrane: Membranes, composed of mucus-secreting cells, that line the surface of body tissue.

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